| 1. Junwan Fan#, Haowen Li#, Lun Kuang#, Zichen Zhao, Wenyan He, Chen Liu, Yongjun Wang*, Steven Y. Cheng*, Wei Chen*.Identification of a Potent Antagonist of Smoothened in Hedgehog Signaling.Cell and bioscience.2021.11(1).46.SCI |
| 2. Barella LF, Rossi M, Zhu L, Cui Y, Mei FC, Cheng X, Chen W, Gurevich VV, Wess J.β-Cell-intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion.J Clin Invest.2019.130.3732-3737.SCI |
| 3. Wang J, Ren XR, Piao H, Zhao S, Osada T, Premont RT, Mook RA Jr, Morse MA, Lyerly HK, Chen W*.Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy.Biochem J.2019.476(3).535-546.SCI |
| 4. Chen W#, Mook RA Jr, Premont RT, Wang J..Niclosamide: Beyond an antihelminthic drug.Cell Signal.2018.41.89-96.SCI |
| 5. Wang J, Mook RA Jr, Ren XR, Zhang Q, Jing G, Lu M, Spasojevic I, Lyerly HK, Hsu D, Chen W*.Identification of DK419, a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth.Bioorg Med Chem.2018.26(20).5435-5442.SCI |
| 6. Mook RA Jr, Ren XR, Wang J, Piao H, Barak LS, Kim Lyerly H, Chen W*.Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/β-catenin signaling with selectivity over effects on ATP homeostasis..Bioorganic & Medicinal Chemistry.2017.25(6).1804-1816.SCI |
| 7. Bhattacharyya J, Ren XR, Mook RA, Wang J, Spasojevic I, Premont RT, Li X, Chilkoti A, Chen W*.Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.Nanoscale.2017.9(34).12709-12717.SCI |
| 8. Chen G, Xie RG, Gao YJ, Xu ZZ, Zhao LX, Bang S, Berta T, Park CK, Lay M, Chen W, Ji RR..b-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration ofpersistent pain.NATURE COMMUNICATIONS.2016.87.207-15.SCI |
| 9. Minyong Chen, Akhil Hegde, Yeon Ho Choi, Barbara S Theriot, Richard T Premont1, Wei Chen, Julia K L Walker* .Genetic Deletion of b-Arrestin-2 and the Mitigation of EstablishedAirway Hyperresponsiveness in a Murine Asthma Model.American Journal of Respiratory Cell and Molecular Biology.2015.53.348-358.SCI |
| 10. Robert A. Mook, Jr., Jiangbo Wang, Xiu-Rong Ren, Minyong Chen, Ivan Spasojevic, Larry S. Barak, H. Kim Lyerly, and Wei Chen*.Structure-Activity studies of Wnt/-betacatenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure..Bioorganic & Medicinal Chemistry.2015.23(17).5829-38.SCI |
| 11. Ren X, Wang J, Osada T, Mook R, Morse M, Lyerly K, Chen W*.Perhexiline promotes HER3 ablation throughreceptor internalization and inhibits tumor growth.Breast Cancer Research.2015.15.17-20.SCI |
