1. Xiaoyi Zhang#, Yifan Yang#, Yuji Wang, Jianhui Wu, Qiongyan Fang, Yaonan Wang, Ming Zhao, Shiqi Peng.(1R,3S)-THCCA-Asn: To show the discovery of selective inhibitor of thrombin by successfully combining virtual screening and biological assay.European Journal of Medicinal Chemistry.2022.242 (2022).114681.SCI |
2. Xiaoyi Zhang, Jinhuan Zhang, Wenchao Liu, Yaonan Wang, Jianhui Wu, Shurui Zhao, Ming Zhao* & Shiqi Peng*.Exploring the action of RGDV‑gemcitabine on tumor metastasis, tumor growth and possible action pathway.Scientific Reports.2020.10.15729.SCI |
3. Xiaoyi Zhang,Yixin Zhang,Yaonan Wang,Jianhui Wu,Haiyan Chen,Ming Zhao*,Shiqi Peng*. Modifying ICCA with Trp-Phe-Phe to Enhance in vivo Activity and Form Nano-Medicine.International journal of nanomedicine.2020.2020.465-481.SCI |
4. Guanyu Li, Tong Wang, Xiaoyi Zhang, Shurui Zhao, Yaonan Wang, Jianhui Wu, Shiqi Peng*,Ming Zhao*.Development of 13-Cys-BBR as an Agent Having Dual Action of Anti-Thrombosis and Anti-Inflammation. Drug Design, Development and Therapy.2020.14.2187–2197.SCI |
5. Mengyu Hou, Manjie Lv, Xiaoyi Zhang, Yaonan Wang, Shurui Zhao, Jianhui Wu, Ming Zhao*, Shiqi peng*.Discovery of novel 6S/12aS-heptachpyridone capable of targeting thrombus and inhibiting thrombosis in vivo.Bioorganic & Medicinal Chemistry Letters.2020.30-19.127440 .SCI |
6. Shurui Zhao,Ze Li,Fei Huang,Jianhui Wu,Lin Gui,Xiaoyi Zhang,Yaonan Wang,Xiaozhen Wang,Shiqi Peng,Ming Zhao*.Nano-scaled MTCA-KKV: for targeting thrombus,releasing pharmacophores, inhibiting thrombosisand dissolving blood clots in vivo.International Journal of Nanomedicine.2019.14.4817–4831.SCI |
7. Jianhui Wu,Yue Cui,Xiaoyi Zhang,Lin Gui,Yaonan Wang,Shiqi Peng,Ming Zhao,*.BCESA: a nano-scaled intercalator capable of targeting tumor tissue and releasing antitumoral β-carboline-3-carboxylic acid.International Journal of Nanomedicine.2019.14.3027–3041.SCI |
8. Wenchao Liu Yujia Mao Xiaoyi Zhang Yaonan Wang Jianhui Wu Shurui Zhao Shiqi Peng Ming Zhao*.RGDV-modified gemcitabine: a nano-medicine capable of prolonging half-life, overcoming resistance and eliminating bone marrow toxicity of gemcitabine.International Journal of Nanomedicine.2019.14.7263–7279.SCI |
9. Juan Feng, Meng Zhou, Xuanzi Lin, An Lu, Xiaoyi Zhang, and Ming Zhao*.Base-Mediated [3 + 4]-Cycloaddition of Anthranils with Azaoxyallyl Cations: A New Approach to Multisubstituted Benzodiazepines..Org. Lett.2019.21.6245−6248.SCI |
10. Shuangling Chen , Zidong Peng, Yuji Wang , Jianhui Wu, Ran An , Rongrong Miao , Ming Zhao * , Shiqi Peng*.Development and activity evaluation of Arg-Gly-Asp-containing antithrombotic conjugate.Journal of Molecular Structure.2019.1198.126816-126824.SCI |
11. Haimei Zhu, Yuji Wang, Ce Song, Qiqi Feng, Jianhui Wu, Shurui Zhao, Lin Gui, Xiaoyi Zhang, Ming Zhao* and Shiqi Peng*.Docking of THPDTPI: to explore P-selectin been a common target of anti-tumor, anti-thrombotic and anti-inflammatory agent.Oncotarget.2018.9 (1).268-281. |
12. Haiyan Chen, An Lu, Xiaoyi Zhang, Lin Gui, Yaonan Wang, Jianhui Wu, Hua Feng, Shiqi Peng* and Ming Zhao*.Design and development of ICCA as dual inhibitor of GPIIb/IIIa and P-selectin receptors.Drug Design, Development and Therapy.2018.12.2097–2110..SCI |
13. Haiyan Chen,Wenjing Wang,Xiaoyi Zhang,Shan Liu,Yaonan Wang,Haimei Zhu,Jianhui Wu,Yuji Wang,Ming Zhao *, Shiqi Peng *.Discovery of DEBIC to correlate P-selectin inhibition and DNA intercalation incancer therapy and complicated thrombosis.Oncotarget.2018.9(63).32119-32133. |
14. Ze Li, Fei Huang, Jianhui Wu, Lin Gui, Xiaoyi Zhang, Yaonan Wang, Shurui Zhao, Xiaozhen Wang, Shiqi Peng*, and Ming Zhao*.Heptapeptide based modification leading to enhancing the action of MTCA on activated platelets, P-selectin, GPIIb/IIIa..Future Medicinal Chemistry.2018.10 (16) .1957-1970.SCI |
15. Jianhui Wu, a§ Haimei Zhu, a§ Guodong Yang,a Jianhong He, *c Yuji Wang, Shurui Zhao, Xiaoyi Zhang, Lin Gui, Ming Zhao*,&Shiqi Peng*.Design and synthesis of nano-scaled IQCA-TAVV as a delivery capable of anti- platelet activation, targeting arterial thrombus and releasing IQCA..International Journal of Nanomedicine.2018.13 .1139-1158 .SCI |
16. Yaonan Wang, Haiyan Chen, Xiaoyi Zhang, Jianhui Wu,Qiqi Feng, Shiqi Peng,, Ming Zhao.*.Dimethyl 2,2′-[2,2′-(ethane-1,1-diyl)bis(1H-indole-3,2-diyl)]-diacetate: a small molecule capable of nano-scale assembly, inhibiting venous thrombosis and inducing no bleeding side effect.International Journal of Nanomedicine.2018.13 .1–10.SCI |
17. Jianhui Wu, § Haimei Zhu, § Guodong Yang, Yuji Wang, Yaonan Wang, Shurui Zhao, Ming Zhao* & Shiqi Peng*.IQCA-TAVV: To get insight of the association between P-selectin, GPIIb/IIIa, IL-2, IL-6 and IL-8 into deep venous thrombosis.Oncotarget.2017.8(53).91391-91401.SCI |
18. Haiping Ma, Ming Zhao*, Yuji Wang, Haimei Zhu, Yaonan Wang, Shurui Zhao, Jianhui Wu, Shiqi Peng*.Cholyl-L-Lysine-carboxyl butyryl adriamycin produgs targeting chemically induced liver injury..J. Mater. Chem. B.2017.5.470-478 .SCI |
19. Yuji Wang, Xinyi Xu, Ce Song, Jianhui Wu, Xi Hu, Haimei Zhu, Xiaoyi Zhang,Yaonan Wang, Lin Gui, Ming Zhao*, and Shiqi Peng*.ATIQCTPC targeting MMP-9: a key step to slowing primary tumor growth and inhibiting metastasis of lewis lung carcinoma in vivo.Oncotarget.2017.8,38.63881-63889 .SCI |
20. Xiaozhen Wang , Yuji Wanga, Jianhui Wu, Lin Gui , Xiaoyi Zhang , Meiqing Zheng , Yaonan Wang, Shurui Zhao , Ze Li , Ming Zhao*, Shiqi Peng*.Docking based design of diastereoisomeric MTCA as GPIIb/IIIa receptor inhibitor..Bioorganic & Medicinal Chemistry Letters.2017.27.5114–5118.SCI |
21. Taiping Gan, Yuji Wang, Ming Zhao*,Jianhui Wu, Jian Yang, and Shiqi Peng* .5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): Showing a strategy of designing drug to block lung metastasis of tumors.Drug Design, Development and Therapy.2016.10.711-721.SCI |
22. Yinghuan Li, Lei Gao, Xi Tan, Feiyang Li, Ming Zhao, Shiqi Peng.Lipid rafts-mediated endocytosis and physiology-based cell membrane traffic models of doxorubicin liposomes..Biochimica Biophysica Acta.2016.1858 (8) .1801-1811.SCI |
23. Haimei Zhu, Yuanbo Song, Yuji Wang, Ming Zhao, Yi Ren, Yaonan Wang, Shurui Zhao, Jianhui Wu and Shiqi Peng.Design, synthesis and evaluation of a novel π–π stacking nano-intercalator as an anti-tumor agent.MedChemComm.2016.7.247-257.SCI |
24. Zhigang Zhao, Xingang Li, Shusen Sun,Shenghui Mei,Ning Ma,Zhongrong Miao,Ming Zhao* , Shiqi Peng*.Impact of genetic polymorphisms related to clopidogrel or acetylsalicylic acid pharmacology on clinical outcome in Chinese patients with symptomatic extracranial or intracranial stenosis..European Journal of Clinical Pharmacology..2016.72.1195-1204.SCI |
25. xueyun jiang,ming zhao*,haimei zhu,shurui zhao,yuanbo song,shiqi,peng*.RGD(F/S/V)-Dex: towards the development of novel, effective, and safe glucocorticoids .Drug Design, Development and Therapy.2016.10.1059-1076.SSCI |
26. Jianhui Wu, Ming Zhao*, Yuji Wang, Yaonan Wang, Haimei Zhu, Shurui Zhao, Shiqi Peng*.A novel lead of P-selectin inhibitor: Discovery, synthesis, bioassays and action mechanism..Bioorg Med Chem Lett.2016.26.4631 - 4636.SCI |
27. Lv Xiaojie, Zhao Ming*, Wang Yuji, Hu Xi, Wu Jianhui, Jiang Xueyue, Li Shan, Cui Chunying, Peng Shiqi*.Loading cisplatin onto 6-mercaptopurine covalently modified MSNS: a nanomedicine strategy to improve the outcome of cisplatin therapy..Drug Design, Development and Therapy.2016.10.3933-3946.SCI |
28. Qiqi Feng, Ming Zhao*,Taiping Gan, Haimei Zhu, Yaonan Wang, Shurui Zhao, Yuji Wang, Jianhui Wu and Shiqi Peng*..DHDMIQK(KAP): a novel nano-delivery system of dihydroxyl-tetrahydro-isoquinoline-3-carboxylic acid and KPAK towards the thrombus..Journal of Materials Chemistry B.2016.4.5991-6003..SCI |
29. Ning Song,Ming Zhao*,Yuji Wang,Xi Hu,Jianhui Wu,Xueyun Jiang,Shan Li,Chunying Cui,Shiqi Peng*. Nanomedical strategy to prolong survival period, heighten cure rate, and lower systemic toxicity of s180 mice treated with mtx/mit. Drug Design Development & Therapy.2016.10. 2701-2711.SCI |
30. Xu Wenyun, Zhao Ming*, Wang Yuji, Zhu haimei, Wang Yaonan, Zhao Shurui, Wu Jianhui, Peng Shiqi*.Design, synthesis, and in vivo evaluations of benzyl Nω-nitro-Nα-(9H-pyrido[3,4-b]indole-3-carbonyl)-L-argininate as an apoptosis inducer capable of decreasing the serum concentration of P-selectin. Medchemcomm.2016.7.1730-1737.SCI |
31. Xi Hu, Ming Zhao*, Yuji Wang, Yaonan Wang, Shurui Zhao, Jianhui Wu, Xiangmin Li and Shiqi Peng*.Tetrahydro-b-carboline-3-carboxyl-thymopentin: a nano-conjugate for releasing pharmacophores to treat tumor and complications.J. Mater. Chem. B.2016.4.1384-1397.SCI |
32. Shuangling Chen, Yuji Wang, Shan Li, Yaonan Wang, Ming Zhao*, Haimei Zhu, Jianhui Wu, Shiqi Peng*.Poly-α,β-aspartyl-Arg-Gly-Asp-Phe: A novel polymeric nanomedicine..MedChemComm.2015.2015, 6, .182-186..SCI |
33. Feng Wang, Shan Li, Yuji Wang, Haimei Zhu , Xiaoyi Zhang , Ming Zhao *, Jianhui Wu and Shiqi Peng *.Enantiomeric diketopiperazines: getting insight into the impact of the configuration on the conformation, nanoimage, u-PA inhibition and anti-metastatic activity.Med. Chem. Commun..2015.2015,6.956-962 .SCI |
34. Shan Li, Yuji Wang, Feng Wang, Yaonan Wang, Xiaoyi Zhang, Ming Zhao*, Qiqi Feng, Jianhui Wu, Shurui Zhao, Wei Wu, Shiqi Peng*.Small molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosis.International Journal of Nanomedicine .2015.2015:10.5273–5292.SCI |
35. Xueyun Jiang, Yuji Wang, Haimei Zhu, Yaonan Wang, Ming Zhao*, Shurui Zhao, Jianhui Wu, Shan Li, Shiqi Peng*.Modifying tetramethyl-nitrophenyl-imidazoline with amino acids: Design, synthesis and 3D-QSAR for improving inflammatory pain therapy..Drug Des Dev Ther.2015.2015, 9, .2329-2342.SCI |
36. Yuji Wang, Jingcheng Tang, Haimei Zhu, Xueyun Jiang,Jiawang Liu,Wenyun Xu,HaipingMa,Qiqi Feng,Jianhui Wu,Ming Zhao*, Shiqi Peng*.Aqueous extract of Rabdosia rubescens leaves: forming nanoparticles, targeting P-selectin, and inhibiting thrombosis.International Journal of Nanomedicine.2015.2015:10.1-14.SCI |
37. Shan Li, Yuji Wang, Ming Zhao*, Jianhui Wu, Shiqi Peng*. BPIC: A novel anti-tumor lead capable of inhibiting inflammation and scavenging free radicals.Bioorg Med Chem Lett.2015.2015, 25.1146-1150.SCI |
38. Nan Xie, Ke Feng, Bin Chen, Ming Zhao, Shiqi Peng*, Liping Zhang, Chenho Tung, Lizhu Wu.Water-soluble copolymeric materials: switchable NIR two-photon fluorescence imaging agents for living cancer cells.J. Mater. Chem. B.2014.2.502-510.SCI |
39. Wenhua Zhao, Yuji Wang, Weijia Hao, Ming Zhao*, Shiqi Peng*.In vitro inhibition of fatty acid synthase by 1,2,3,4,6-penta-O-galloyl-β-D-glucose plays a vital role in anti-tumour activity.BBRC.2014.445.346-351.SCI |
40. Nan Xie, Ke Feng, Bin Chen,b Ming Zhao*, Li-Ping Zhang, Chen-Ho Tung, Li-Zhu Wu, Shiqi Peng*.A modular designed copolymer with antithrombotic activity and imaging capability.ChemComm.2014.50.9535-9542.SCI |
41. Shaoming Jin,#Yaonan Wang#, Haimei Zhu, Yuji Wang, Shurui Zhao, Ming Zhao,* Jiawang Liu,Jianhui Wu, Wen Gao, and Shiqi Peng*.Nanosized Aspirin-Arg-Gly-Asp-Val: elivery of Aspirin to Thrombus bythe Target Carrier Arg-Gly-Asp-Val etrapeptide.Acsnano.2013. .NO. XX ’ 000–000 ’ XXXX.SCI |
42. Wenjing Wang#, Chenjie Fang, Xiaozhu Wang, Yuxi Chen, Wei Feng, Chunhua Yan, Ming Zhao*, Shiqi Peng*.Modifying mesoporous silica nano-particle to avoid the metabolic deactivation of 6-mercaptopurine and methotrexate in combinatorial chemotherapy.Nanoscale .2013.5.6249 - 6253.SCI |
43. Haimei Zhu*, Yuji Wang, Yaonan Wang, Shurui Zhao, Ming Zhao*, Lin Gui, Wenyun Xu, Xiangyun Amy Chen, Yanming Wang, Shiqi Peng*.Folded conformation, cyclic pentamer, nano-structure and PAD4 binding mode of YW3-56. J Phys Chem C.2013.117.10070-10078.SCI |
44. Haimei Zhu#, Yuji Wang, Ming Zhao*, Jianhui Wu, Xiaoyi Zhang, Guodong Yang, Shiqi Peng*.Energy minimized crystal structures of P-selectins based on molecular dynamics simulation: Leading to two average structures capable of designing anti-thrombotic agents..MedChemComm.2013.4.1066 - 1072.SCI |
45. Yuji Wang#, Jianhui Wu, Guifeng Kang, Ming Zhao,* Lin Gui, Ning Li, Li Peng, Xiaoyi Zhang, Li Li and Shiqi Peng*.Novel nano-materials, RGD-tetrapeptide-modified 17b-amino-11a-hydroxyandrost-1,4-diene-3-one: synthesis, self-assembly based nano-images and in vivo anti-osteoporosis evaluation.J. Mater. Chem.2012.22.4652–4659.SCI |
46. Li Li#, Ming Zhao,* Wenhao Li, Yuji Wang, Zhuge Zhang, Ran An and Shiqi Peng*.Self-complexation and complexation-controlled target cancer therapy.Med. Chem. Commun.2012.3.1059 - 1061.SCI |
47. Gui Lin#, Zhao Ming*, Wang Yuji, Wang Yinye, Qin Yang, Li Li, Shiqi Peng*.Synthesis, nano-features, ex vivo anti-platelet aggregation and in vivo antithrombotic activities of poly-α,β-DL-aspartyl-L-arginine.Med. Chem. Commun.2012.3.102-108..SCI |
48. uji Wang#,Guifeng Kang,Jiawang Liu,Ming Zhao,*Jianhui Wu, Xiaoyi Zhang,Ye Li, Xiaobo Zhong, Yifan Yang and Shiqi Peng*.Novel potassium N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxylhex-1-yl]-L-amino acid dichloroplatinates(II) with high anti-tumor activity and low side reaction.Metallomics.2012.4.441–447.SCI |
49. Li Li#, Ming Zhao*, Wenhao Li, Yuji Wang, Chunna Liu,Zhuge Zhang, Songchun Su, Shiqi Peng*.1 pH-Dependent nanostructure based on isoquinoline-cyclodextrin conjugate for thrombosis therapy.Nanomedicine: Nanotechnology, Biology, and Medicine.2012.8(7).1216–1222.SCI |
50. anxia Xu, Yuji Wang, Ming Zhao*, Baoguang Hou, Li Peng, Meiqing Zheng, Jianhui Wu, Shiqi Peng*.Lead detoxification activities and ADMET hepatotoxicities of a class of novel 5-(1-carbonyl-L-amino-acid)-2,2-dimethyl-[1,3]dithiolane-4-carboxylic acids.Bioorganic & Medicinal Chemistry Letters .2011.21.1754–1757.SCI |
51. Yanxia Xu, Yuji Wang, Ling Wang, Ming Zhao,* Xiaoyi Zhang, Xiaomin Hu, Baoguang Hou, Li Peng,Meiqing Zheng, Jianhui Wu, and Shiqi Peng*.Lead Detoxification Activities of a Class of Novel DMSA_Amino Acid Conjugates.Chem. Res. Toxicol.2011.24.979–984.SCI |
52. Liu Liu, Lei Wei, Yifan Yang, Ming Zhao,* Xiaoyi Zhang, Meiqing Zheng, Yuji Wang and Shiqi Peng*.A class of novel AA-Trp-Trp-OBzl: synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and intercalation mechanism.Med. Chem. Commun..2011.2011(2).126-131.SCI |
53. Wenjing Wang, Ming Zhao,* Yuji Wang, Jiawang Liu, Jianhui Wu, Guifeng Kang and Shiqi Peng*.{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1Hindol-3-yl}-acetic acid methyl ester (MIAM): Its anti-cancer efficacy andintercalation mechanism identified via multi-model system.Molecular BioSystems..2011.7.766-772.SCI |
54. Ning Li, Guifeng Kang, Lin Gui, *Ming Zhao, Wenjing Wang, Jianwei Zhang, Yan-Feng Yue, *Shiqi Peng..Novel Cu(II)-RGD-octapeptides: Synthesis, coordination mode, in vitro anti- platelet aggregation/in vivo anti-thrombotic evaluation and correlation of sequence with nano-structure.Nanomed-Nanotechnol.2011.7(4).403–409.SCI |
55. Yuji Wang, Xueyun Jiang, Jiawang Liu, Ming Zhao,*Guifeng Kang, Jianhui Wu, Li Peng and Shiqi Peng*.HPLC-MS aided PC12 cell systems: to quantitatively monitor the conversion of nitronyl nitroxide in biological systems with and without NO..Mol. BioSyst..2011.7.1678–1683 .SCI |
56. Hong Wang, Le Peng, Ming Zhao, Jiawang Liu, Xiaoyi Zhang, Yuji Wang,Jianhui Wu, Li Li, Shiqi Peng..2-Substituted (S)-2-(3,3-dimethyl-1-oxo-10,10a-dihydroimidazo[1,5-b]isoquino-. Bioorganic & Medicinal Chemistry.2011.9(2).871-882 .SCI |
57. Guifeng Kang, Ming Zhao, Xiaoyi Zhang, Li Peng, Chunbo Li, Wei Mao, Weidong Ye, Shiqi Peng..A class of novel conjugates of substituted purine and Gly-AA-OBzl: Synthesis and evaluation of orally analgesic activity .Bioorganic & Medicinal Chemistry Letters, .2010.20(20).6157-6160.SCI |
58. Jianhui Wu, Chunyu Li, Ming Zhao *, Wenjing Wang, Yuji Wang, Shiqi Peng *,.A class of novel carboline intercalators: Their synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and 3D QSAR analysis.Bioorganic & Medicinal Chemistry .2010.18.6220–6229 .SCI |
59. Lin Gui, Ming Zhao*,Yinye Wang, Yang Qin, Jiangyuan Liu, Shiqi Peng*.Synthesis, nanofeatures, in vitro thrombus lysis activity and in vivo thrombolytic activity of poly-α, β-aspartyl-L-alanine.Nanomedicine .2010.5.703–714 .SCI |
60. Ming Zhao, Yuji Wang, Caixia Huo, Jiawang Liu, Chunyu Li, Xiaoyi Zhang, Li Peng, and Shiqi Peng*.Lead Detoxification Activity and ADMET Hepatotoxicity of N-(r-LArabino-furanos-1-yl)-L-cysteine.Chem. Res. Toxicol 23(7) .2010.23(7).xxx-xxx.SCI |
61. Jianhui Wu, Ming Zhao & Shiqi Peng.Quinazolin-4(3H)-ones capable ofupregulating the expression of endogenous apolipoprotein A-1.Expert Opin. Ther. Patents.201.213(.431-435.SCI |
62. Ming Zhao, Caixia Huo, Yuji Wang, Chongyu Li, Xiaoyi Zhang, Li Peng, Shiqi Peng*.Stereoselective synthesis of Novel N-(α-L-arabinose-1-yl)-L-amino Acids..Tetrahedron: Asymmetry.2009.20.247-258.SCI |
63. Ming Zhao, Jiangyuan Liu, Xiaoyi Zhang, Li Peng, Chunyu Li, Shiqi Peng*.3D QSAR of novel estrogen-RGD peptide conjugates: Getting insight into structural dependence of anti-osteo- porosis activity and side effect of estrogen in ERT.Bioorg. Med. Chem.2009.17.3680-3689..SCI |
64. Fei Huang, Ming Zhao*, Xiaoyi Zhang, Chao Wang, Keduo Qian, Jen-Yun Kuo, Susan Morris- Natschke, Kuo-Hsiung Lee, Shiqi Peng*.Synthesis, DNA Intercalation and 3D QSAR Analysis of cis-2,4,5-Trisubstituted-1,3-dithiolanes as a Novel Class of Antitumor Agents.Bioorg. Med. Chem.2009.17.6085–6095.SCI |
65. Jianhui Wu, Ming Zhao*, Keduo Qian, Kuo-Hsiung Lee, Susan Morris-Natschke, Shiqi Peng*.Novel N-(3-carboxyl-9-benzylcarboline-1-yl) ethylamino acids: Synthesis, antitumor evaluation, intercalating determination, 3D QSAR analysis and docking investigation.Eur. J. Med. Chem.2009.44.4153–4161.SCI |
66. Yang Jian, Zhiyu Tang, Yinye Wang,, Shiqi Peng*.Polyaspartoyl L-arginine protects endothelial cells against injury.European Journal of Pharmacology .2008.599.96-101.SCI |
67. Li Li, Guohui Cui, Ming Zhao,* Yuji Wang, Hong Wang, Wei Li, and Shiqi Peng*.Assembly of _-Cyclodextrin with 3S-Tetrahydro-_-carboline-3-carboxylic Acid and.J. Phys. Chem.2008.112.12139–12147.SCI |
68. Ming Zhao, Zheng Li, Li Peng, Yu-Rong Tang, Chao Wang, Ziding Zhang, Shiqi Peng*.A new class of analgesic agents toward prostacyclin receptor inhibition: synthesisbiological studies and QSAR analysis of 1-hydroxyl-2-substitutedphenyl-4,4,5,5-tetramethylimidazolines.Eur. J. Med. Chem.2008.43.1048-1058.SCI |
69. Lanrong Bi, Ming Zhao, Keli Gu, Chao Wang, Jingfang Juc, Shiqi Peng*.Toward the develop- ment of chemoprevention agents (III): Synthesis and anti-inflammatory activities of a new class of 5-glycylamino-2-substituted-phenyl-1,3-dioxacycloalkanes.Bioorg. Med. Chem.2008.16.1764-1774.SCI |
70. Meiqing Zheng , Xiaoyi Zhang , Ming Zhao ,*, Heng Wei Chang *, Wei Wang , Yuji Wang , Shiqi Peng*.(3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novelantithrombotic agents: Synthesis, bioassay, 3D QSAR, and ADME analysis.Bioorganic & Medicinal Chemistry .2008.16. 9574–9587.SCI |
71. Xue Ren, Guohui Cui, Ming Zhao, Chao Wang, Shiqi Peng*.Coordination of Thrombolytic Pro-Ala-Lys peptides with Cu (II): Leading to nano-scale self-assembly, increase of thrombolytic activity and additional vasodilation.The Journal of Physical Chemistry .2008.112.8174-8180.SCI |
72. Mei Yang, Guohui Cui, Ming Zhao*, ChaoWang, LiliWang,Hu Liu, Shiqi Peng*.The effect of complexation of Cu(II) with P6A peptide and itsanalogs on their thrombolytic activities.International Journal of Pharmaceutics.2008.362.81-87.SCI |
73. Jiawang Liu, Guohui Cui, Ming Zhao*, Chunying Cui, Jingfang Ju, Shiqi Peng*.Design, synthesis, MES-SA/Dx5 cell assay and SAR of 2,2-dimethyl-3-[1’-substi-tutedacetyloxybenzyl]-4- oxoimidazo[3’,5’:2,3]tetrahydro-β-carbolines.Bioorg. Med. Chem.2007.15.7773-7778. .SCI |
74. Guofeng Wu, Lanrong Bi, Ming Zhao*, Chao Wang, Michèle Baudy-Floc’h , Jingfang Ju, Shiqi Peng*.Toward breast cancer resistance protein (BCRP) inhibitors: Design, synthesis of a series of new simplified fumitremorgin C analogues.Tetrahedron.2007.63.5510-5528.SCI |
75. Jiawang Liu, Guofeng Wu, Guohui Cui, Wei-Xuan Wang, Ming Zhao*, Chao Wang, Ziding Zhang, Shiqi Peng*.A new class of anti-thrombosis hexahydropyrazino[1’,2’:1,6]- pyrido[3,4-b]indole-1,4-dions: Design, synthesis, logK determination and QSAR analysis.Bioorg. Med. Chem.2007.15.5672-5693. |
76. Ming Zhao, Xin Jia, Chao Wang, Qin Li, Kexiang Zhou, Lili Wang, Hu Liu and Shiqi Peng*.PAK: An Essential Motif for Forming β-Turn Structures and Exhibiting Thrombolytic Effect for P6A and Its Analogs.Biochem. Cell Biol..2007.85.730-740.SCI |
77. Ming Zhao, Zheng Li, Li Peng, Yu-Rong Tang, Chao Wang, Ziding Zhang, Shiqi Peng*.Novel 1-Oxyl-2-substitutedphenyl-4,4,5,5-tetramethylimidazolines: Synthesis, Selectively Analgesic Action and QSAR analysis.Bioorg. Med. Chem. .2007.15.2815-2826.SCI |
78. Ming Zhao, Zheng Li, Yihui Wu, Chao Wang, Ziding Zhang, Shiqi Peng*.Studies on LogP, Retention Time and QSAR of 2-Substitutedphenylnitronyl Nitroxides as Free Radical Scavenger.Eur. J. Med. Chem..2007.42.955-965.SCI |
79. Ming Zhao, Lanrong Bi, Wei Bi, Chao Wang, Zhe Yang, Jingfang Ju and Shiqi Peng*..Synthesis of new class dipeptide analogues with improved permeability and antithrombotic activity.Bioorg. & Med. Chem. .2006.14.4761-4774.SCI |
80. Ming Zhao, Lanrong Bi, Wei Wang, Chao Wang, Michèle Baudy-Floc’h, Jingfang Ju, Shiqi Peng*..Synthesis and cytotoxic activities of β-carboline amino acid ester conjugates.Bioorg. & Med. Chem. .2006.14.6998-7010.SCI |
81. Yihui Wu, Lanrong Bi, Wei Bi, Zeng Li, Ming Zhao, Chao Wang, Jingfang Ju, Shiqi Peng*..Novel 2-Substitutednitronyl Nitroxides as Free Radical Scavengers: Synthesis, Biological Evaluation and Structure- Activity Relationship.Bioorg. & Med. Chem.2006.14.5711-5720.SCI |
82. Keli Gu, Lanrong Bi, Ming Zhao, Chao Wang, Cheryl Dolan, Michael C. Kao, Jeffrey B.-H. Tok and Shiqi Peng*.Stereoselective synthesis and anti-inflammatory activities of 6- and 7-membered dioxacycloalkanes.Bioorg. & Med. Chem.2006.14.1339-1347.SCI |
83. Lanrong Bi, Yue Zhang, Ming Zhao, Chao Wang, Priscilla Chan, Jeffrey B.-H. Tok, Shiqi Peng*.Novel Synthesis and Anti-inflammatory Activities of 2,5-disubstituted-dioxacycloalkanes.Bioorg. & Med. Chem.2005.13.5640-5646.SCI |
84. Ming Zhao, Junling Liu, Chao Wang, Lili Wang, Hu Liu, Shiqi Peng.Synthesis and Biological Activity of Nitronyl Nitroxide Containing Peptides.J Med. Chem.2005.48.4285-4292.SCI |
85. Ming Zhao, Chao Wang, Yanfen Wu, Kexiang Zhou, and Shiqi Peng*.Synthesis and Thrombolytic Activity of Carboline-3-carboxylic Acid Modified Metabolites of ARPAK.Preparative Biochemistry & Biotechnology.2004.34.55-74.SCI |
86. Ming Zhao, Chao Wang, Shiqi Peng*.The composition and sequence specificity of Pro-Ala-Lys-OH for the throm- bolytic activities of P6A and related oligopeptides.Bioorg. & Med. Chem.2004.12.2275-2286.SCI |