1. Luo D#, Liu X#, Jiang L, Guo Z, Lv Y, Tian X, Wang X, Cui S, Wan S, Xu X*, Li X*, Qu X*.Rational Design, Synthesis, and Biological Evaluation of Novel S1PR2 Antagonists for Reversing 5-FU-Resistance in Colorectal Cancer.J Med Chem .2022.65(21).14553-14577.SCI |
2. Sun SY, Hu XT, Yu XF, Zhang YY, Liu XH, Liu YH, Wu SH, Li YY, Cui SX*, Qu XJ*.Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting to Mis18alpha in colorectal cancer.Br J Pharmacol.2021.178(11).2351-2369.SCI |
3. Zhang YH, Shi WN, Wu SH, Miao RR, Sun SY, Luo DD, Wan SB, Guo ZK , Wang WY , Yu XF, Cui SX*, Qu XJ*.SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulating H3K56ac-mediated DPD expression.Oncogene.2020.39(29).5214-5227.SCI |
4. Yu-Hang Zhang, Dong-Dong Luo, Sheng-Biao Wan*,Xian-Jun Qu*.S1PR2 inhibitors potently reverse 5-FU resistance by downregulating DPD.Pharmacological Research.2020.155.104717.SCI |
5. Song ZY,Wang F, Cui SX, Gao ZH*, Qu XJ*.CXCR7/CXCR4 heterodimer-induced histone demethylation: a new mechanism of colorectal tumorigenesis.Oncogene.2019.38(9).1560-1575.SCI |
6. Yu X, Wang D, Wang X, Sun S, Zhang Y, Wang S, Miao R, Xu X, Qu X*.CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p.J Exp Clin Cancer Res.2019.38(1).32.SCI |
7. Wang SQ, Yang XY, Xinfeng Yu, Cui SX*, Qu XJ*.Knockdown IGF-1R triggers viral RNA sensors MDA-5- and RIG-I-mediated mitochondrial apoptosis in colonic cancer cells.Molecular Therapy—Nucleic Acids.2019.16.105-117.SCI |
8. Wang SQ, Yang XY, Cui SX*, Gao ZH, Qu XJ*. Heterozygous knockout insulin-like growth factor-1 receptor (IGF-1R) regulates mitochondrial functions and prevents colitis and colorectal cancer.Free Radic Biol Med.2019.134.87-98.SCI |