| 1. Yanan Li a,Keqin Li b,Ting Pan a,Qiaobo Xie b,Yuyao Cheng a,Xinfeng Wu b,Rui Xu b,Xiaohui Liu b,Li Liu c,Jiangming Gao c,Wenmin Yuan c
, Xianjun Qu b,Shuxiang Cui a.Translocation of IGF-1R in endoplasmic reticulum enhances SERCA2 activity to trigger Ca2+ER perturbation in hepatocellular carcinoma.Acta Pharm Sin B.2023.13(9).3744-3755.SCI（含SCIE） |
| 2. Qiaobo Xie a,Yanyan Chu b,Wenmin Yuan c,Yanan Li d,Keqin Li a,Xinfeng Wu a,Xiaohui Liu a,Rui Xu a,Shuxiang Cui d
, Xianjun Qu a.Activation of insulin-like growth factor-1 receptor (IGF-1R) promotes growth of colorectal cancer through triggering the MEX3A-mediated degradation of RIG-I.Acta Pharm Sin B.2023.13(7).2963-2975.SCI（含SCIE） |
| 3. D Luo, X Liu, L Jiang, Z Guo, Y Lv, X Tian, X Wang, S Cui, S Wan, X Qu, X Xu, X Li.Rational Design, Synthesis, and Biological Evaluation of Novel S1PR2 Antagonists for Reversing 5-FU-Resistance in Colorectal Cancer.J Med Chem.2022.65(21).14553-14577.SCI（含SCIE） |
| 4. Rong-Rong Miao, Sheng Zhan, Shu-Xiang Cui, Xian-Jun Qu#.Intestinal aberrant sphingolipid metabolism shaped-gut microbiome and bile acids metabolome in the development of hepatic steatosis.The FASEB Journal.2022.36. .SCI（含SCIE） |
| 5. Shi-Yue Sun, Xue-Tao Hu, Xin-Feng Yu, Yue-Ying Zhang, Xiao-Hui Liu, Yuan-Hang Liu, Shu-Hua Wu, Yang-Yang Li, Shu-Xiang Cui, Xian-Jun Qu .Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting to Mis18alpha in colorectal cancer.Br J Pharmacol.2021.178(11).2351-2369.SCI（含SCIE） |
| 6. Rong-Rong Miao, Sheng Zhan, Xue-Tao Hu, Wen-Min Yuan, Li-Juan Wu, Shu-Xiang Cui, Xian-Jun Qu.Myricetin and M10, a myricetin-3-O-β-d-lactose sodium salt, modify composition of gut microbiota in mice with ulcerative colitis.Toxicology Letters.2021.46. .SCI（含SCIE） |
| 7. Dongdong Luo, Yuhang Zhang, Shuang Yang, Xiaochen Tian, Yan Lv, Zhikun Guo, Xiaochun Liu, Gaitian Han, Shuai Liu, Wenyu Wang, Shuxiang Cui, Xianjun Qu, Shengbiao Wan.Design, synthesis and biological evaluation of sphingosine-1- phosphate receptor 2 antagonists as potent 5-FU-resistance reversal agents for the treatment of colorectal cancer.European Journal of Medicinal Chemistry.2021.65. .SCI（含SCIE） |
| 8. Yu-Hang Zhang, Dong-Dong Luo, Sheng-Biao Wa, Xian-Jun Qu*.S1PR2 inhibitors potently reverse 5-FU resistance by downregulating DPD.Pharmacological Research.2020.155.104717.SCI（含SCIE） |
| 9. Zhang,Yu-Hang[1];Shi,Wen-Na[2];Wu,Shu-Hua[3];Miao,Rong-Rong[1];Sun,Shi-Yue[1];Luo,Dong-Dong[4];Wan,Sheng-Biao[4];Guo,Zhi-Kun[5];Wang,Wen-Yu[1];Yu,Xin-Feng[1];Cui,Shu-Xiang[5];Qu,Xian-Jun[1].SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulating H3K56ac-mediated DPD expression.Oncogene.2020.39(29).5214-5227.SCI（含SCIE） |
| 10. Yu-hang Zhang, Shu-xiang Cui, Sheng-biao Wan, Shu-hua Wu, Xian-jun Qu.Increased S1P induces S1PR2 internalization to blunt the sensitivity of colorectal cancer to 5-fluorouracil via promoting intracellular uracil generation.Acta Pharmacologica Sinica.2020.42. .SCI（含SCIE） |
